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Background: Atopic dermatitis is a non-communicable skin disorder characterized by intense itching. It is relapsing, recurring, and can have a negative impact on the quality of life of patients and their family members. Atopic dermatitis occurs most often in early infancy and childhood. Atopic dermatitis can occur if there is dysregulation of IgE resulting in a breakdown of the epidermal barrier. There are several factors that trigger the occurrence of atopic rheumatism in children, which can come from environmental factors or medical history.
Aim: For this reason, this study aims to analyze the similarity of output regarding the magnitude of risk factors for atopic dermatitis in children.
Methods: This study was analyzed using a meta-analysis using PRISMA, where there were 7 of 8654 articles that met the criteria for analysis. Meanwhile, the data presentation was carried out using a forest plot with a random effect statistical model.
Results: The presence of pets, children living in environments that have pets (cats or dogs) are known to increase the risk of atopic dermatitis by 5 times compared to children living in environments that do not have animals. pet. The health history factor seen from exclusive breastfeeding, where babies who are exclusively breastfed are significantly less likely to experience atopic dermatitis by 12.5 times compared to babies who are not exclusively breastfed.
Conclusion: Not giving exclusive breastfeeding and pets affect atopic dermatitis in children (p<0,05).
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2. Nutten S. Atopic dermatitis: global epidemiol-ogy and risk factors. Ann Nutr Metab. 2015;66(Suppl. 1):8–16.
3. Pyun BY. Natural history and risk factors of atopic dermatitis in children. Allergy Asthma Immunol Res. 2015;7(2):101–5.
4. Al-Adawiyah R, Putera AM, Astari L, Ariyanto FC. Determinant factors of recurrence atopic dermatitis symptoms in children: A cross-sectional study. Ann Med Surg. 2021;70:102847.
5. Gold MS, Kemp AS. 6. Atopic disease in child-hood. Med J Aust. 2005;182(6):298–304.
6. Asher MI, Stewart AW, Mallol J, Montefort S, Lai CKW, Aït-Khaled N, et al. Which popula-tion level environmental factors are associat-ed with asthma, rhinoconjunctivitis and ec-zema? Review of the ecological analyses of ISAAC Phase One. Respir Res. 2010;11(1):1–10.
7. Strachan DP. Allergy and family size: a riddle worth solving. Clin Exp allergy J Br Soc Aller-gy Clin Immunol. 1997;27(3):235–6.
8. Legy YFS. GAMBARAN TINGKAT PENGE-TAHUAN IBU TENTANG PEMBERIAN ASI EK-SKLUSIF DI KELURAHAN REJOSARI SEMIN GUNUNGKIDUL TAHUN 2021. Poltekkes Ke-menkes Yogyakarta; 2021.
9. Rana MR, Ety A, Dian Isti A. Dermatitis Atopik pada Anak dengan Riwayat Pemberian ASI Ekslusif. J Agromed Unila. 2017;4(2):283–6.
10. Aditianti A, Djaiman SPH. Meta Analisis: Pengaruh Anemia Ibu Hamil Terhadap Berat Bayi Lahir Rendah. J Kesehat Reproduksi. 2020;11(2):163–77.
11. Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Reprint—preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Phys Ther. 2009;89(9):873–80.
12. Budiastuti M, Setya Wandita S. Exclusive breastfeeding and risk of atopic dermatitis in high risk infant. J Med Sci (Berkala Ilmu Kedokteran). 2007;39(04).
13. Forouzanfar MH, Afshin A, Alexander LT, Anderson HR, Bhutta ZA, Biryukov S, et al. Global, regional, and national comparative risk assessment of 79 behavioural, environ-mental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1659–724.
14. Farajzadeh S, Shahesmaeili A, Bazargan N, Poorkani ZM, Karaminejad Z, Aghaei H, et al. Relationship between duration of breast-feeding and development of atopic dermati-tis. J Pakistan Assoc Dermatologists. 2011;21(2):80–6.
15. Eichenfield LF, Tom WL, Berger TG, Krol A, Paller AS, Schwarzenberger K, et al. Guide-lines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014;71(1):116–32.
16. Salo PM, Zeldin DC. Does exposure to cats and dogs decrease the risk of allergic sensiti-zation and disease? J Allergy Clin Immunol. 2009;124(4):751–2.
17. Endaryanto A. Memahami dan mengurai kompleksitas manajemen alergi pada anak Indonesia. Airlangga University Press; 2021.
18. Junita Widani N. HUBUNGAN MANIFES-TASI ALERGI DENGAN RIWAYAT PENGGUNAAN ANTIBIOTIK PADA BALITA DI PUSKESMAS BENDAN KOTA PEKALONGAN. Universitas Airlangga; 2016.
19. Budiastuti, Martaviani. Exclusive breastfeed-ing and risk of atopic dermatitis in high risk infant. Berkala Ilmu Kedokteran, Volume 39, No. 4, Desember 2007: 192-198 Berkala Ilmu Kedokteran Vol. 39, No. 4, Desember 2007: 192-198
20. Kansen, Hannah. Risk factors for atopic dis-eases and recurrent respiratory tract infec-tions in children. Pediatric Pulmonology. 2020;55:3168–3179
21. Ho, Ciao-Lin. The prevalence and risk factors of atopic dermatitis in 6e8 year-old first graders in Taipei. Pediatrics and Neonatology (2019) 60, 166-171
22. Akan, Ayşegül. Risk factors of severe atopic dermatitis in childhood: single-center expe-rience. The Turkish Journal of Pediatrics 2014; 56: 121-126
23. Munasir, Zakiudin. The role of allergic risk and other factors that affect the occurrence of atopic dermatitis in the first 6 months of life. Asia Pac Allergy 2011;1:73-79