Main Article Content


Introduction: Nutritional status is often associated with mortality and disease morbidity, including liver cirrhosis. Assessment of Tricep Skin Fold (TSF) and mid-arm muscle circumference (MAMC) is an easy parameter of nutritional status.

Objective: This study aims to determine the relationship between nutritional status and clinical outcomes in patients with liver cirrhosis.

Methods: The study used a retrospective cohort observational design with a sample of 57 patients with liver cirrhosis with various etiologies. The data comes from the results of anthropometric measurements of patients in the poly or inpatient ward and interviews regarding the history of the disease and complications experienced during the last month. Data analysis used the Chi-square test with a 95% Confidence Interval (CI), p < 0.05, to analyze the relationship between nutritional status (TSF and MAMC) with clinical outcomes of liver cirrhosis (hematemesis melena, degree of esophageal varices grade Hepatic encephalopathy (HE) and degree of ascites).

Results: Based on the TSF and MAMC values, data on cirrhotic patients who experienced nutritional status with the “low” criteria were 33.3% and 57.89%, respectively. The 'low” TSF value significantly correlates with the HE incidence (p = 0.049) with the RR value of 0.461. The relationship between MAMC and the incidence of ascites was statistically significant (0.004), with an RR value of 0.462.

Conclusion: Nutritional status affects the incidence of HE and ascites in liver cirrhosis patients

Article Details

How to Cite
Supriono, S., & Dianita Mayasari , E. (2023). The Correlation between Nutritional Status and Clinical Outcome of Liver Sirosis Patients at RSUD Dr. Saiful Anwar Malang. Jurnal Klinik Dan Riset Kesehatan, 2(3), 325-330.


1. Suzuki K, Endo R, Kato A. Nutritional Status in Liver Cirrhosis. In: Liver Cirrhosis-Update and Current Challenges. IntechOpen; 2017. page 139–54.
2. European Association for the Study of the Liver. EASL Clinical Practice Guidelines on nutrition in chronic liver disease. Journal of hepatology 2019;70(1):172–93.
3. Romeiro FG, Augusti L. Nutritional assessment in cirrhotic patients with hepatic encephalopathy. World Journal of Hepatology 2015;7(30):2940.
4. Nunes G, Santos CA, Barosa R, Fonseca C, Barata AT, Fonseca J. Outcome and nutritional assessment of chronic liver disease patients using anthropometry and subjective global assessment. Arquivos de gastroenterologia 2017;54:225–31.
5. Bishop CW, Bowen PE, Ritchey S. Norms for nutritional assessment of American adults by upper arm anthropometry. The American Journal of Clinical Nutrition 1981;34(11):2530–9.
6. Wang X, Lin SX, Tao J, Wei XQ, Liu YT, Chen YM, et al. Study of liver cirrhosis over ten consecutive years in Southern China. World journal of gastroenterology: WJG 2014;20(37):13546.
7. Guy J, Peters MG. Liver disease in women: the influence of gender on epidemiology, natural history, and patient outcomes. Gastroenterology & hepatology 2013;9(10):633.
8. Gonzalez-Chagolla A, Olivas-Martinez A, Ruiz-Manriquez J, Servín-Rojas M, Kauffman-Ortega E, Chávez-García LC, et al. Cirrhosis etiology trends in developing countries: Transition from infectious to metabolic conditions. Report from a multicentric cohort in central Mexico. The Lancet Regional Health-Americas 2022;7:100151.
9. D’angelo G. Role of hepcidin in the pathophysiology and diagnosis of anemia. Blood research 2013;48(1):10.
10. Nga WTB, Ndam AN, Offiala NA, Bagnaka SAFE, Malongue A, Tzeuton C, et al. Nutritional Assessment of Nonhospitalized Patients with Liver Cirrhosis in 04 Reference Hospitals in Cameroon. 2022;
11. Traub J, Reiss L, Aliwa B, Stadlbauer V. Malnutrition in Patients with Liver Cirrhosis. Nutrients 2021;13(2):540.
12. Chapman B, Sinclair M, Gow PJ, Testro AG. Malnutrition in cirrhosis: More food for thought. World journal of hepatology 2020;12(11):883.