A Retrospektif Study Clinicopathology Profile of Salivary Glands Tumor at the Anatomical Pathology Installation of Dr. Saiful Anwar Malang Hospital in 2017-2021 Period
DOI:
https://doi.org/10.11594/jk-risk.03.1.3Keywords:
histopathology, Salivary gland tumorAbstract
Abstract
Background: Cases of salivary gland tumors are relatively rare. There are not many data that explain the prevalence of salivary gland tumor incidence in Indonesia.
Objective: This study aims to determine the clinicopathological profile of salivary gland tumors based on case incidence, age, gender, location and histopathological subtype at the Anatomical Pathology Installation of Dr. Saiful Anwar Hospital Malang in 2017-2021.
Methods: This research is a quantitative descriptive study. Data was collected from medical records from 2017 to 2021 at the Anatomical Pathology Installation of Saiful Anwar Hospital, Malang. All subjects in this study were all clinical data of patients with tumor located salivary gland (parotid, submandibular, sublingual/cavum oris).
Results and Discussion: There were 162 cases of salivary gland tumors from 2017-2021, malignant neoplasm 57 (35%), benign neoplasm 60 (37%) and non neoplasm 45 (28%). The distribution of the incidence of cases per year is not the same and does not always increase. There was a relationship between the increase in cases of malignancy with increasing age. There is no relationship between increasing cases of salivary gland tumors and malignancy with gender. The most common locations for salivary gland tumors and malignant neoplasm in parotid gland. The most malignant neoplasm is mucoepidermoid carcinoma 11 (19.2%), the most benign neoplasm is pleomorphic adenoma 38 (63.3%), the most non-neoplastic cases is inflammation and abscess 34 (75.5%).
Conclusion: Salivary gland tumors are rare cases. Cases of malignancy increase in adults and the elderly. The most common location in the parotid gland with the most cases of malignant neoplasm is mucoepidermoid carcinoma and the most benign neoplasms is pleomorphic adenoma.
Keywords: Salivary gland tumor, histopathology.
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References
Cunha, J. L. S., Hernandez-Guerrero, J. C., de Almeida, O. P., Soares, C. D. & Mosqueda-Taylor, A. Salivary Gland Tumors: A Retrospective Study of 164 Cases from a Single Private Practice Service in Mexico and Literature Review. Head Neck Pathol. 15, 523–531 (2021).
Sentani, K. et al. Characteristics of 5015 salivary gland neoplasms registered in the hiroshima tumor tissue registry over a period of 39 years. J. Clin. Med. 8, 1–13 (2019).
Merung, M. P. J. Gambaran Histopatologi Tumor Kelenjar Liur Di Manado Periode Juli 2010 – Juli 2013. e-CliniC 2, (2014).
Lisnawati, L., Stephanie, M. & Hamdani, C. Diagnostic accuracy and cytomorphology analysis of fine-needle aspiration of salivary glands. Med. J. Indones. 21, 92–96 (2012).
Sowa, P. et al. A Review of Selected Factors of Salivary Gland Tumour Formation and Malignant Transformation. Biomed Res. Int. 2018, (2018).
Noel, L. et al. Epidemiology of salivary gland tumours in an Eastern Caribbean nation: A retrospective study. Ann. Med. Surg. 36, 148–151 (2018).
Bobati, S. S., Patil, B. V. & Dombale, V. D. Histopathological study of salivary gland tumors. J. Oral Maxillofac. Pathol. 21, 46–50 (2017).
Jeferson, E., Septiman, S. & Faruk, M. Epidemiology Major Salivary Gland Tumour in Eastern Indonesia. Int. J. Med. Rev. Case Reports 5, 1 (2020).
Swarnkar, N., Venkataraman, S. & Saravanam, P. K. Salivary gland tumours: a retrospective study at a tertiary care centre in South India. Int. J. Otorhinolaryngol. Head Neck Surg. 7, 825 (2021).
Ito, F. A., Ito, K., Vargas, P. A., de Almeida, O. P. & Lopes, M. A. Salivary gland tumors in a Brazilian population: A retrospective study of 496 cases. Int. J. Oral Maxillofac. Surg. 34, 533–536 (2005).
Collazo-Fernández, L., Campo-Trapero, J., Cano-Sánchez, J., García-Martín, R. & Ballestín-Carcavilla, C. Retrospective study of 149 cases of salivary gland carcinoma in a Spanish hospital population. Med. Oral Patol. Oral Cir. Bucal 22, e207–e213 (2017).
Wang, X. D., Meng, L. J., Hou, T. T. & Huang, S. H. Tumours of the salivary glands in northeastern China: A retrospective study of 2508 patients. Br. J. Oral Maxillofac. Surg. 53, 132–137 (2015).
Mejía-Velázquez, C. P., Durán-Padilla, M. A., Gómez-Apo, E., Quezada-Rivera, D. & Gaitán-Cepeda, L. A. Tumors of the salivary gland in Mexicans. A retrospective study of 360 cases. Med. Oral Patol. Oral Cir. Bucal 17, 183–189 (2012).
da Silva, L. P. et al. Salivary gland tumors in a Brazilian population: A 20-year retrospective and multicentric study of 2292 cases. J. Cranio-Maxillofacial Surg. 46, 2227–2233 (2018).
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