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Dec 3, 2021
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Feb 4, 2022
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Abstract

Background: Sinonasal neoplasms are uncommon. Adenoid cystic carcinoma (ACC) is the 2nd commonest sinonasal malignancy, characterized by an indolent and slow growth but relatively high local recurrence and distant metastasis rate. Surgical management followed by adjuvant radiation therapy is the mainstay of treatment for sinonasal ACC. Surgical approach is modified according to the tumor size and location.In general, prognosis of sinonasal neoplasms is poor. Factors that contribute the overall prognosis such as type of histopathological findings, absent of perineural or perivascular invasion and distant metastases, site of tumour, age of patient and treatment modality.


Aim: To report a case of nasal ACC with regional metastases treated with surgical management followed radiation therapy.


Case Report: A 70-years-old man came to the ENT clinic at RSUD dr. Saiful Anwar Malang with right nasal obstruction and history of right epistaxis for 12 months. The patient underwent surgical using lateral rhinotomy approach with Moure’s incision, histopatological specimen revealed a cribiform type ACC.


Conclusion: Surgical management and adjuvant radiation therapy is the gold standard for sinonasal ACC Longterm evaluation is a mandatory according to the high incidence of local recurrence and distant metastases of sinonasal ACC.

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How to Cite
Sudarmanto, Y., Soehartono, Angelina, A., Yudhanto, H., & Putri, A. (2022). Adenoid Cystic Carcinoma Nasal. Jurnal Klinik Dan Riset Kesehatan, 1(2), 134-144. https://doi.org/10.11594/jk-risk.01.2.8

References

1. Ghani NMSNA, Shukri NM, Mohamad A. 2 Case reports of sinonasal adenoid cystic carcinoma: Review of the literature on surgical approaches. Egypt J Ear, Nose, Throat Allied Sci [Internet]. 2016;17(3):173–6.
DOI: 10.1016/j.ejenta.2016.07.006
2. Thompson LDR, Bishop JA. Head and neck pathology: A volume in the series: Foundations in diagnostic pathology. In: Goldblum JR, editor. Head and Neck Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Philadelphia: Elsevier; 2018:57–61.
3. Amit M, Binenbaum Y, Sharma K, et al. Adenoid cystic carcinoma of the nasal cavity and paranasal sinuses: A meta-analysis. J Neurol Surgery, Part B Skull Base. 2013;74(3):118–25.
4. Thompson LDR, Penner C, Ho NJ, et al. Sinonasal Tract and Nasopharyngeal Adenoid Cystic Carcinoma: A Clinicopathologic and Immunophenotypic Study of 86 Cases. Head Neck Pathol. 2014;8(1):88–109.
5. Unsal AA, Chung SY, Zhou AH, et al. Sinonasal adenoid cystic carcinoma: a population-based analysis of 694 cases. Int Forum Allergy Rhinol. 2017;7(3):312–20.
6. Shishodia S, Narayan U, Sharma S. Annals of clinical case reports an unusual case of adenoid cystic carcinoma of nasal. Rem Publ LLC. 2020;5:1–3.
7. Coca-Pelaz A, Rodrigo JP, Bradley PJ, et al. Adenoid cystic carcinoma of the head and neck - An update. Oral Oncol. 2015;51(7):652–61.
8. Ferlito A. Cervical lymph node metastasis in adenoid cystic carcinoma of the sinonasal tract, nasopharynx, lacrimal glands and external auditory canal: A collective international review. J Laryngol Otol. 2016;130(12):1093–7.
9. Dhingra H, Baliyan A, Narang S, et al. Adenoid cystic carcinoma of nasal cavity in an adolescent male - A Rare presentation. J Krishna Inst Med Sci Univ. 2018;7(2):107–10.
10. Tasoulas J, Divaris K, Theocharis S, et al. Impact of tumor site and adjuvant radiotherapy on survival of patients with adenoid cystic carcinoma: A seer database analysis. Cancers (Basel). 2021;13(4):1–16.
11. Seong SY, Hyun DW, Kim YS, et al. Treatment outcomes of sinonasal adenoid cystic carcinoma: 30 cases from a single institution. J Cranio-Maxillofacial Surg. 2014;42(5):2–6.
12. Chang CF, Hsieh MY, Chen MK, et al. Adenoid cystic carcinoma of head and neck: A retrospective clinical analysis of a single institution. Auris Nasus Larynx [Internet]. 2018;45(4):831–7. Tersedia pada: https://doi.org/10.1016/j.anl.2017.10.009
13. Tai S, Chien C, Tai C, et al. N Asal S Eptum a Denoid C Ystic C Arcinoma : a C Ase R Eport. J Med. 2007;23(8).
14. Choi Y, Kim SB, Yoon DH, et al. Clinical Characteristics and Prognostic Factors of Adenoid Cystic Carcinoma of the Head and Neck. Laryngoscope. 2013;123(6):1430–8.
15. Lupinetti AD, Roberts DB, Williams MD, et al. Sinonasal adenoid cystic carcinoma: The M. D. Anderson Cancer Center experience. Cancer. 2007;110(12):2726–31.
16. Tummidi S, Kothari K, Patil R, et al. Sinonasal adenoid cystic carcinoma-role of on-site FNAC: A case report. BMC Ear, Nose Throat Disord. 2018;18(1):4–8.
17. Seok J, Lee DY, Kim WS, et al. Lung metastasis in adenoid cystic carcinoma of the head and neck. Head Neck. 2019;41(11):3976–83.
18. Lorini L, Ardighieri L, Bozzola A, et al. Prognosis and management of recurrent and/or metastatic head and neck adenoid cystic carcinoma. Oral Oncol [Internet]. 2021;115(Januari):105213. DOI:10.1016/j.oraloncology.2021.105213
19. Demiray M, Sahinbas H, Atahan S, et al. Successful treatment of c-kit-positive metastatic Adenoid Cystic Carcinoma (ACC) with a combination of curcumin plus imatinib: A case report. Complement Ther Med. 2016;27:108-113.
doi:10.1016/j.ctim.2016.06.009