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Feb 25, 2025
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Abstract
Peripheral arterial disease is a disorder caused by decreased blood flow to the extremities. The process of atherosclerosis generally causes it and manifests as claudication. In addition to optimal medical and endovascular therapy, non-pharmacological management of PAP has been proven to be effective in reducing symptoms and improving walking ability and quality of life. Walking exercise can increase blood flow, which allows oxygen and nutrients to reach the muscles more efficiently and triggers the angiogenesis process. Supervised exercise programs in PAP patients are considered important as primary therapy to improve functional capacity and quality of life for long-term management.
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This work is licensed under a Creative Commons Attribution 4.0 International License.
How to Cite
Lestari, D., & Tjahjono, C. (2025). The Role of Supervised Exercise Therapy of People With Lower Extremity Peripheral Artery Disease. Jurnal Klinik Dan Riset Kesehatan, 4(2), 117-130. https://doi.org/10.11594/jk-risk.04.2.6
References
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3. Mardiansyah. Data rekam medis Pusat Jantung Nasional Harapan Kita. Jakarta; 2012.
4. White, C. Intermitten claudication. NEJM 2007;356:1241-1250.
5. Murphy TP, Cutlip DE, Regensteiner JG, Mohler ER, Cohen DJ, Reynolds MR, et al. Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease : six-month outcomes from the claudication: exercise versus endoluminal revascularization (CLEVER) study. Circulation 2012;125:130- 139.
6. Stewart KJ, Hiatt WR, Regensteiner JG, Hirsch AT. Exercise training for claudication. NEJM 2002;347(24):1941-1950.
7. Tendera M, Aboyans V, Bartelink M-L, Baum-gartner I, Clement D, Collet J-P, et al. ESC guidelines on the diagnosis and treatment of peripheral arterial diseases.
8. European Heart Journal 2011; 32(22):2851- 2906. Milani RV, Lavie CJ. The role of exercise training in peripheral arterial disease. Vasc Med 2007;12:351-358.
9. Halliday A, Bax JJ. The 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society for Vascular Surgery (ESVS). European journal of vascular and endovascular surgery. 2018 Mar 1;55(3):301-2.
10. Rooke TW, Hirsch AT, Misra S, Sidawy AN, Beckman JA, Findeiss LK, et al. 2011
11. ACC/AHA Focused update of the guidelines for the management of patients with peripheral arterial disease (updating the 2005 guideline). Circulation 2011; 124:2020- 2045.
12. Parr BM, Derman EW. The effect of exercise training in patients with peripheral vascular disease-a review. SAJSM 2006;18(4):116-121.
13. Watson L, Ellis B, Leng GC. Exercise for inter-mitten claudication. Cochrane Database Syst Rev 2008;4:1-55.
14. McDermott MM, Ades P, Guralnik JM, et al: Treadmill exercise and resistance training in patients with peripheral arterial disease with and without intermittent claudication: a ran-domized controlled trial. JAMA 2009;301:165-170.
15. Spronk S, Bosch JL, Veen HF, Hoed PT, Hunink MGM. Intermitten claudication: functional ca-pacity and quality of life after exercise training or percutaneous transluminal angioplasty-systematic review. RSNA 2005;235:833-842.
16. Spronk S, Bosch JL, Veen HF, Hoed PT, Pat-tynama PMT, Hunink MGM. Intermitten claudication: effectiveness of endovascular revascularization versus supervised hospital- based exercise training-randomized controlled trial. RSNA 2009;250(2):586-595.
17. Hiatt WR, Wolfel EE, Meier RH, Regensteiner JG. Superiority of treadmill walking exercise versus strength training for patients with pe-ripheral arterial disease. Implications for the mechanism of the training response. Circula-tion 1994;90:1866- 1874.
18. Hamburg NM, Balady GJ. Exercise rehabilita-tion in peripheral artery disease : functional impact and mechanism of benefits. Circulation 2011; 123:87-97.
19. Stewart KJ, Ratchford EV, Williams MA. Exer-cise for restoring health and preventing vascu-lar disease. In : Blumenthal RS, Foody. JM, Wong ND, editors. Preventive cardiology: a companion to braunwald’s heart disease. Phil-adelphia. Elsevier Saunders;2011:541-551.
20. Treat-Jacobson D, McDermott MM, Beckman JA, Burt MA, Creager MA, Ehrman JK, Gardner AW, Mays RJ, Regensteiner JG, Salisbury DL, Schorr EN. Implementation of supervised exercise therapy for patients with symptomatic peripheral artery disease: a science advisory from the American Heart Association. Circulation. 2019 Sep 24;140(13):e700-10